Lectures

The One Health Intellectual Exchange "Philosophy to Practical Integration of Human, Animal and Environmental Health", an IEG discussion series, is sponsored by the Triangle Global Health Consortium One Health Collaborative. It is designed to enhance collaborations between physicians, veterinarians, researchers and other local / global health professionals by increasing public awareness of the interconnectedness of people, animals and the environment.

One Health Intellectual Exchange Group Course:

Philosophy to Practical Integration of Human, Animal, and Environmental Health

Spring Semester 2014

Cross-listed at Duke, NCSU, and UNC

Tuesdays, 5:30-7:30 pm

North Carolina Biotechnology Center

2014

Module 1:  Introduction to One Health

 

Jan 14             From 2/3 to One: An MD’s Perspective on One Health

Peter Rabinowitz, MD

Department of Environmental and Occupational Health Sciences

Director, Human Animal Medicine Project
University of Washington

Module 2:  Environmental Health / Ecology

Jan 21             A multidisciplinary approach to parasitic diseases

Armando (Emico) Gonzalez, PhD

Professor, Departmento de Salud Animal y Salud Publica

Universidad Nacional Mayor de San Marcos

Cysticersosis Working Group of Peru

Jan  28            Water contamination associated with shale gas exploration and hydraulic fracturing in the United States

Avner Vengosh, PhD

Professor of Geochemistry and Water Quality

Nicholas School of the Environment, Duke University

Feb 4               One Health, One Welfare: Supporting human livelihoods through improved health and welfare of working animals

Andrew Stringer, BVSc PhD MRCVS

Director of Veterinary Programmes

Society for the Protection of Animals Abroad

Module 3:  Zoonoses and Emerging Infectious Diseases

Feb 11             Evolutionary Anthropology (title TBD)

Charlie Nunn, PhD

Professor, Department of Evolutionary Anthropology & Global Health Institute

Duke University

Feb 18            Hemotropic Mycoplasma (title TBD)

                       Ricardo Magi, PhD, MS

                       Research Associate Professor, Department of Clinical Sciences

                       College of Veterinary Medicine

                       North Carolina State University

Module 4: Food and Water Safety

Feb 25            Tracking pathogens in water (title TBD)

                       Jill Stewart, PhD

                       Assistant Professor, Department of Environmental Sciences & Engineering

                       UNC- Chapel Hill, Deputy Director, UNC Galapagos Initiative

                       And

Microorganisms & microbially-mediated processes in coastal land-water interfaces  

Mike Piehler, PhD

Associate Professor, Department of Marine Sciences

UNC- Chapel Hill, Program Head, Estuarine Ecology and Human Health

UNC Coastal Studies Institute

Mar 4              Food safety (title TBD)

                        Barb Kawolsky, PhD

                        Assistant Professor, Department of Food, Bioprocessing & Nutrition Sciences

                        North Carolina State University

                        CEO, Center for Foodborne Illness Research and Prevention

Mar 11           Title TBD

                        George Gunn,  MRCVS

                        Novartis, Vaccine Development

Module 5: The Human and Animal Bond: The Tie that Binds

                                                                                                                                   

Mar 18            Assessing Attributable Risks in Environmental Health Science (tentative title)

Ellen Silbergeld, PhD

Professor, Department of Environmental Health Sciences

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

Editor-in-Chief, Environmental Research HPM

Mar 25            Influence of pets on human health (title TBD)

                        Harold Herzog, PhD

                        Professor, Department of Psychology

                        Western Carolina University

                        Author of Some We Love, Some We Hate, and Some We Eat

                        And

                        Pit Bulls: The Controversy over Breed-Specific Legislation (tentative title)

                        Bronwen Dickey

                        Essayist and Journalist

                        Contributor to: The Oxford America, Newsweek, Outside, Sport Driver, Scuba Diving, The Independent Weekly, and the Sab Francisco Chronicle

 Module 6:  Disease Surveillance, Informatics, and Disaster Preparedness

           

April 1             Vector Borne Diseases and Surveillance (title TBD)

Carl Williams, DVM, DACVPM

N.C. Department of Health and Human Services

State Public Health Veterinarian

 April 8            Title TBD

Larry D. Michael, REHS, MPH

NC Department of Health and Human Services

Branch Head, Food Protection and Facilities Branch

Division of Public Health

And

Food Safety for Mass Gatherings and Special Events (tentative title)

Donna Wanucha, REHS

Regional Retail Food Specialist

FDA/Southeast Region

Module 7:  Benefits of Comparative Medicine 

April 15           Mesenchymal Stem Therapy for Repair of Cartilage in the Equine Athlete and Other Treatment Modalities (tentative title)

C. Wayne McIlwraith, BVSc, MS, PhD, DSc, FRCVS

                        Diplomate ACVS, Diplomate ECVS, Diplomate ACVSMR

                        University Distinguished Professor

                        Barbara Cox Anthony University Endowed Chair in Orthopaedics

                        Director of Orthopaedic Research Center

                        Colorado State University

Module 9:  One Health in the Bigger Picture: Policy, Education, Conclusions 

April 22           Embracing the One Health Paradigm in Approaching Complex Public Health Problems

Gregory Gray, MD, MPH, FIDSA

Director, Global Pathogens Laboratory

University of Florida Emerging Pathogens Institute

2012

Module 1: Introduction to One Health

Jan 10 What is One Health all about? 

Panel of NC One Health Collaborative Steering Committee Members

Chris Woods, MD, MPH, Associate Professor in the Departments of Medicine and Pathology at Duke

Suzanne Kennedy-Stoskopf, DVM, PhD, DACZM, Research Professor of Wildlife Infectious Disease, Department of Clinical Sciences at NCSU CVM

Vivian Doelling, PhD, Senior Scientist, NICEATM, Integrated Laboratory Systems, Advisory Board for the Master’s of Microbial Biotechnology program at NCSU

Jan 17 The One Health Journey: Personal Epiphanies & the History of One Health 

Cheryl Stroud, DVM, PhD, Chair, North Carolina One Health Collaborative Steering Committee & One Health Intellectual Exchange Group

Rear Admiral William Stokes, DVM, DACLAM, National Institute of Environmental Health Science, Director, NTP Interagency Center for the Evaluation of Alternative Toxicological Methods; Executive Director, Interagency Coordinating Committee on the Validation of Alternative Methods

Module 2: Environmental Health / Ecology

Jan 24 The Neem Tree: Nature’s Bio-Defense at its Best and Tropical Forest Regeneration in Costa Rica

Peter Radtke, PhD, Grifols Pharmaceuticals, Chairman and CEO of JustNeem 

Magda Radtke, COO, Development and Production of JustNeem
Erin Lindquist, PhD, Assistant Professor & Environmental Sustainability Advisor at Meredith College

Jan 31 Pollutants and Environmental Health and Mercury dynamics in aquatic systems: linking natural resource management with human health policy

Joel Meyer, PhD, Assistant Professor of Environmental Toxicology at Duke

Derek Aday, PhD, Associate Professor of Biology at NCSU

Module 3: The Human and Companion Animal Bond: The Tie that Binds

Feb 7 The Links Between Animal Abuse & Family Violence: Implications for the Medical Professions

Phil Arkow, Coordinator, The National Link Coalition; Link Consultant, ASPCA; Link Consultant, Animals & Society Institute; Chair, Animal Abuse & Family Violence Prevention Project, The Latham Foundation

Feb 14 Meaningful Uses of Man’s Best Friends 

Larry Glickman, VMD, PhD, Professor of Epidemiology and Public Health in the Department of Emergency Medicine at UNC 

Jacqueline Bailey, BS candidate, Biology and International Studies minor at Meredith College

Module 4: Zoonoses and Emerging Infectious Diseases

Feb 21 Center of Excellence for Emerging and Zoonotic Animal Diseases and One Health

Jürgen Richt, DVM, PhD, Collaborator/Associate Professor Veterinary Microbiology and Preventive Medicine at Iowa State University; Veterinary Medical Officer National Animal Disease Center

Feb 28 The West Nile Virus Outbreak of 1999: A Compelling Argument for One Health

Tracey S. McNamara, DVM, DACVP, Professor of Pathology at Western University of Health Sciences College of Veterinary Medicine

Module 5: Food / Water Safety

Mar 13

WaSH and One Health
Jamie Bartram, PhD, Professor Environmental Sciences & Engineering at UNC 

Microbial impacts of animal agriculture on water quality and human health risks
Mark Sobsey, MS, PhD, Professor, Department of Environmental Sciences and Engineering, Director, Environmental Microbiology Laboratory at UNC

March 20

A One Health approach to the leading cause of death in children
William Pan, PhD, Assistant Professor of Global Environmental Health at Duke

Public health issues related to industrial food animal production

Beth Feingold, MPH, PhD, Postdoctoral Fellow at Johns Hopkins University

Module 6: Disease Surveillance, Informatics, Disaster Preparedness

March 27 Emergence of a zoonotic tropical disease in the United States: visceral leishmaniasis

Christine Petersen, DVM, PhD, Assistant Professor of Veterinary Pathology at Iowa State University CVM

April 3

One Health Core Competencies - Building Capacity for Response to Emerging Pandemic Threats

Felicia Nutter, DVM, PhD, DACZM, Research Assistant Professor at Tufts University Cummings SVM, USAID Grantee, RESPOND Project Senior Technical Officer 

The USAID PREDICT Project: Building a global early warning system for emerging zoonoses

Chris Whittier, DVM, PhD, Associate Veterinarian at Smithsonian

Module 7: Benefits of Comparative Medicine

April 10 From Four Legs to Two - Translating Research Findings to Therapy of Spinal Cord Injury

Dogs and Spinal Cord Injury - Another Role for Man's Best Friend
Natasha Olby, VetMB, PhD, DACVIM, Professor, Neurology at NCSU CVM

The Dalfampridine Story - The Making of a Medicine
Andrew Blight, PhD, Chief Scientific Officer Acorda Therapeutics

April 17 Going to the dogs … for a new model organism of non-Hodgkin lymphoma

Steven Suter, VMD, MS, PhD, DACVIM, Assistant Professor, Oncology at NCSU CVM 

Kristy Richards, MD, PhD, Assistant Professor Department of Genetics at UNC

Module 8: One Health in the Bigger Picture: Policy, Education, Conclusions

April 24 One Health: A Concept for the 21st Century

Laura Kahn, MD, MPH, MPP, Department of Science & Global Security at Princeton University

Session 1, 2011: Introduction to the Concept of One Health: Initiative, History, Relevant Institutions, Goals

Panel Discussion led by Members of the TGHC One Health Collaborative Steering Committee:

Larry Glickman, VMD, DrPH, (UNC Chapel Hill)

Suzanne Kennedy Stoskopf, DVM, PhD (NC State University)

Barrett Slenning, DVM, MVPH (NC State University)

Cheryl Stroud. DVM, PhD, TGHC One Heath Collaborative Chair

Chris Woods, MD, MPH (Duke University)

Session 2, 2011 (Jan.18): Relevance of Global Environmental Change for Understanding Future Dynamics of Animal & Human Health with Dr. Jason West

Speaker: 
Dr. Jason West, Assistant Professor, Department of Environmental Science & Engineering, University of North Carolina

Objectives: 

• Global Climate Change – Understanding the Problem.  I hope that students will gain a general understanding of the causes, impacts, and potential solutions to global climate change, emphasizing how scientific understanding of climate change was gained through history.
• Impacts of Climate Change on Human Health.  As climate affects health through several different mechanisms, we will first identify those different mechanisms and explore how research is moving toward quantified impacts and plans for adaptation.
• Some Current Research on Climate – Air Quality – Human Health Linkages.  I will show results of some research from my lab connecting climate, air quality, and health problems, and will use methane mitigation as an example of a possible “win-win”.

Session 3: Jan 25, 2011: A Tale of Two Species: Co-evolution and Domestication of Dogs and People

Featuring speaker/discussion leader Dr. Alan Beck, Director, Center of the Human - Animal Bond and Dorothy N. McAllister Professor of Animal Ecology, School of Veterinary Medicine, Purdue University

Domestication of the dog involves both humans and dogs developing together. One can guess that some of the earliest reasons for dog domestication were practical; dogs were guardians, were sentinels for the presence of other humans or animals, perhaps to be used to captured or restrained prey species, and perhaps to be eaten themselves when necessary. When looking at domestication as a naturally occurring event, and not simply artificial selection, it is very possible that dogs were, first and foremost created to be the companions of their creators and significantly influenced the survival and culture of human beings. The presentation will discuss the mechanisms of domestication, the hypothesis of the dog-human pack; mastering and loving, and the implication of domestication for humans and animals.

Session 4: The biology and control of dengue virus: Immune responses, disease dynamics and genetic modification of the mosquito vector

Dr. Aravinda Desilva, Dengue Hemorrhagic Fever: a case study of a disease in which the human immune response can be beneficial or harmful

Learning goals:

1) Understand that many infectious diseases have complex presentation with severe cases only representing a small fraction of infections.

2) Understand the antibody dependent enhancement hypothesis of severe dengue

3) Be up to date with current approaches being used to develop dengue vaccines and the practicalities of deploying a dengue vaccine

Dr. Katia Koelle, Mathematical models for understanding the ecological and evolutionary dynamics of dengue

 Learning goals:

1) Develop a basic understanding of compartmental disease models and what they are useful for.

2) Understand how herd immunity and the immunological interactions between dengue’s four serotypes can affect patterns of dengue incidence.

3) Understand how dengue models can be used to evaluate and suggest vaccination strategies.

Dr. Fred Gould, Genomic approaches for manipulating mosquito vectors of malaria and dengue

 Learning goals:

1) Have a very basic understanding of transgenic strategies for manipulating mosquitoes.

2) Be able to discuss the interaction between vector manipulation and vaccine use.

3) Be aware of ethical and operational issues related to use of transgenic mosquitoes.

Session 5: Feb 8, 2011: Rabies from multiple perspectives: A One Health Exemplar

Dr. Carl Williams, Rabies: A disease with a comprehensive medical, legal, and public health framework

Learning Objectives:

1.    To understand the rationale for the existence of a legal framework for rabies control.

2.    To know the individual roles and responsibilities of animal owners, bite victims, animal control officers, physicians and veterinarians when dealing with rabies exposures.

3.    To understand basic principles of rabies exposure risk assessment to ensure people exposed receive appropriate care.

Dr. Charles Rupprecht, Rabies: an Epitome of the One-Health Concept

Learning Objectives:

1)    To appreciate the value of basic surveillance and laboratory-based diagnosis conducted upon animal reservoirs and their critical role for decision making in human rabies exposures.

2)    To understand the utility of experimental rabies models, as surrogates in pathogenesis studies for relevant disease prevention and treatment in humans and other animals.

3)    To comprehend the historical importance of focusing upon control via vaccine-induced herd immunity, in domestic animals and wildlife, as a barrier to human infection, and a productive means of ultimate disease elimination.

Dr. G. Robert Weedon, The role of animal population control in human rabies prevention

Learning objectives:

1) To recognize the unique demographics of dog populations, and their role as the principal reservoir of rabies, in developing countries.

2) To appreciate the value of canine sterilization and mass vaccination campaigns in preventing human rabies in communities where the dog is the principal reservoir of rabies.

3) To increase awareness of the potential for non-surgical sterilants and their use in rabies prevention programs in areas where animal overpopulation and human rabies is a problem

Peter Costa, Health Communication: Bridging Gaps for Rabies Prevention

Learning Objectives:

1.    To list three reasons why rabies remains a neglected zoonotic disease on a global scale

2.    To describe the pivotal role of health communication and community education in effective and sustainable rabies prevention programs

3.    To formulate novel approaches to building partnerships, engaging hard-to-reach populations and overcoming barriers to health communication