About the One Health Intellectual Exchange Series

This interdisciplinary course will introduce the concept of One Health as an increasingly important approach to a holistic understanding of the prevention of disease and the maintenance of both human and animal health. The list of topics will include a discussion of bidirectional impact of animal health on human health, the impact of earth’s changing ecology on health, issues of food and water security and preparedness, and the benefits of comparative medicine. Learning objectives include 1) to describe how different disciplines contribute to the practice of One Health, 2) to creatively design interdisciplinary interventions to improve Global Health using a One Health model, and 3) to interact with One Health-relevant professionals in the Triangle and beyond. The course aims to include students from Duke, UNC and NC State from diverse disciplines relevant to One Health, including: human medicine, veterinary medicine, environmental science, public health, global health, public policy, and others.

Tuesday, January 28, 2014

From 2/3 to One Health: an MD’s Perspective. Tuesday January 14th

The One Health Discussion series continued this year with Peter Rabinowitz, MD, MPH who is an Associate Professor in the Department of Environmental and Occupational Health Science and the Department of Global Health at the University of Washington, where he directs the Human Animal Medicine Project. http://deohs.washington.edu/hamp/  He completed a Family Medicine residency at UC San Francisco and a fellowship in General Preventive Medicine/Occupational and Environmental Medicine at the Yale School of Medicine. 

The Human Animal Medicine Project explores the linkages between human, animal, and environmental health including zoonotic infectious disease at the human-animal interface, animals as ‘sentinels’ of environmental health hazards, and clinical collaboration between human health care providers and veterinarians in a species-spanning approach. A goal of the Project is to serve as an incubator and organizer of research, training, and clinical activities at the University of Washington related to the human-animal-ecosystem interface.

Dr. Rabinowitz began the discussion by providing a working definition: “One Health (formerly called One Medicine) is dedicated to improving the lives of all species—human and animal—through the integration of human medicine, veterinary medicine and environmental science.”  He provided a history of One Health through examples from Virchow, Osler, and Schwabe.

Dr. Rabinowitz emphasized the emerging and reemerging infections from vector-borne or zoonotic means.  He explained the intensification of agriculture, resulting in large farms of pigs and chickens, with chickens reaching numbers into the 20 billion. He also noted how deforestation and changing water resources are changing the global environment. He emphasized how 50% of US households have pets, with most pets being in households with children.

It was noted how the concept of ‘One Health’ has gained endorsements from the WHO, CDC, USDA, OIE, FAO, AMA, AVMA, CPHA, NCCID, and the Gates Foundation.  It spans the concepts of individual health, population health, and ecosystem health encompassing Zoonotic infections along with Comparative Medicine/Translational Medicine.

He endorsed the book “Zoobiquity: The Astonishing Connection Between Human and Animal Health” by Barbara Natterson-Horowitz and Kathryn Bowers.

Dr. Rabinowitz noted the disparity of One Health Programs, which are more prevalent in Veterinary schools than Medical schools.

Several case presentations were made.  The first involved a dog with a mass in his spinal column and its owner with non-specific gastrointestinal symptoms that progressed to altered mental status and fever of unknown origin.  A discussion ensued from all fields as to the differential and appropriate course of care.  Quite quickly, a differential of Rocky Mountain Spotted Fever was offered and a review of the pathophysiology was covered.  In the case example, the Veterinarian received the diagnosis from the CDC through pathology and conveyed the information to the Physician resulting in the corrected treatment and resolution of symptoms. A discussion followed as to how the case could have been handled more efficiently and effectively.  Most discussion focused on developing a better monitoring infrastructure and communication network.

A second case was presented involving a pregnant woman with cats exhibiting anorexia, dehydration, ataxia, tremor, and hypersalivation for 3 weeks which was ineffectively treated with an H2 blocker for reflux. The cats where admitted to a veterinary hospital where they were found to be anemic with lead levels that was lethal to one of the cats even after chelation therapy.  The pregnant woman was instructed to follow-up with her own doctor and was found to have a lead level of 40mcg/dL. It turned out that she was stripping old paint with a blowtorch while preparing her house for the baby.  A discussion ensued as to how animals can act as sentinels and how the case could have been handled differently.  The conversation focused on better avenues of communication.

There was an emphasis on barriers to One Health including the following:  Professional Segregation, ‘Us vs Them’ attitude, need for evidence, training structure, time needed for paradigm shifts, and location.   There should be a shift from an ‘Us vs Them’ mentality to a ‘Shared Risk’ viewpoint.

The cases were reviewed with this vantage point with a postulated shared electronic medical record that would be able to alert an MD for a possible differential prompting a quicker diagnosis and treatment with cost savings.

New Competencies for Human Health were suggested including:
  • Understanding of shared environmental risks
  • Including veterinarians in health care
  • Ability to interpret comparative medical information
  • Awareness of the role of zoonotic infection in both acute and chronic disease; including smoldering infection
  • Awareness of the relevance of a shared microbiome

There was emphasis on developing evidence for clinical relevance of animal disease events to humans through retrospective review of veterinary medical charts.  The example of feline asthma was given as sentinels of air quality.

The session concluded with reference back to the Human Animal Medicine Project and the Zoobiquity conference in Seattle. http://zoobiquity.com/events/upcoming-events/


Post authored by Johann Hsu, MD

No comments:

Post a Comment